G3Edge Documentation

website·Indexed 31 days ago

https://www.g3bio.com/

Documentation for G3Edge, a platform for managing and visually exploring multiomics data. It includes the DataHub module for data exploration, the Projects module for viewing analysis results, and the g3tools command suite for tasks such as RunAnalysis, ConvertData, and LoadSingleCell. The platform supports bulk and single-cell RNA-Seq data processing via analytics integrations like DESeq2, Seurat, and FGSEA.

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What's inside G3Edge

  1. Overview of G3Edge Data Management and Visualization

    G3Edge is a browser-based platform designed for the storage, manipulation, and visualization of large-scale genomic and omics datasets. It enables users to perform cohort analysis and identify clinical correlates interactively with high performance, often retrieving data from thousands of samples in less than one second.
  2. Overview of tSNE Plot for high-dimensional data visualization

    tSNE (t-distributed Stochastic Neighbor Embedding) plot is an unsupervised, non-linear dimensionality reduction technique. It is primarily used to visualize high-dimensional datasets, such as single-cell RNA-Seq, by projecting them into a lower-dimensional space (typically 2D or 3D) while preserving local structures.
  3. Overview of G3Edge Multiomics Framework

    G3Edge is a browser-based premium framework developed by G3Bio designed for multiomics data management and exploration. It provides capabilities to store and visualize large-scale "omics" data, execute analytics pipelines, monitor jobs, and manage projects.
  4. Overview of G3Edge multiomics platform

    G3Edge is a versatile web platform designed for storing, hosting, and visually exploring internal and external multiomics data. It is built to handle large-scale datasets containing millions of samples or cells, enabling computational and clinical scientists to explore, validate, and share results on a single platform to ensure reproducibility and transparency.
  5. Overview of the G3Edge Projects module

    The Projects module in G3Edge is integrated with the Analytics module and serves as a container for final analysis results, such as tables and charts. A single project can aggregate results from one or multiple analysis runs. Users can perform the following actions within the Projects module: create new projects, append additional data and views to existing projects, and share projects with other users.
  6. Visualize gene set enrichment using a Gene-set Enrichment Plot

    A Gene-set enrichment plot is used to visualize the enrichment of a pre-defined gene set within a ranked list of genes. This visualization helps identify whether a specific set of genes is overrepresented at the top or bottom of a ranked list (e.g., ranked by fold change or p-value).
  7. Understand Volcano Plot visualization

    A Volcano Plot is a specialized scatterplot used to visualize the relationship between statistical significance (represented by the P value) and the magnitude of change (represented by the fold change).
  8. Manage analysis results in G3Edge Projects

    The Projects module is integrated with the Analytics module, allowing users to store and view results (such as tables or charts) generated from one or more analysis runs.
  9. Visualize sample distribution with a Box Plot

    Use a Box Plot to visualize and compare the sample distribution across different groups of a categorical variable.
  10. Visualize relative gene expression with Heatmap View

    The Heatmap View is used to visualize and analyze the relative gene expression levels across a specific group of samples, allowing developers or researchers to identify patterns of expression across different biological contexts.